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Diamondbacks vs Cardinals Prediction, Odds, and Picks for May 25, 2025

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Diamondbacks vs Cardinals Prediction, Odds, and Picks for May 25, 2025

The St. Louis Cardinals and Arizona Diamondbacks are set to conclude their three-game series at Busch Stadium on Sunday, May 25, 2025, at 2:15 p.m. ET. With the Cardinals leading the series 2-0, they aim for a sweep, while the Diamondbacks look to salvage a win.

Pitching Matchup: Sonny Gray vs. Brandon Pfaadt

The Cardinals will send right-hander Sonny Gray (5-1, 4.02 ERA) to the mound. Gray is coming off a dominant performance, pitching six scoreless innings against the Detroit Tigers. His experience and recent form make him a formidable opponent.

Opposing him is Diamondbacks’ right-hander Brandon Pfaadt (7-3, 3.81 ERA), who leads MLB in wins. Pfaadt has delivered quality starts in six of his ten outings this season, showcasing consistency and resilience.

Team Performance and Key Players

The Cardinals (29-23) have been strong at home, boasting an 18-8 record at Busch Stadium. Offensively, Lars Nootbaar leads the team with seven home runs and 25 RBIs, while Brendan Donovan tops the batting average chart at .321.

The Diamondbacks (26-26) are looking to break a three-game losing streak. Ketel Marte has been a bright spot, contributing eight home runs this season. However, the team needs a collective effort to overcome the Cardinals’ momentum.

Betting Odds and Predictions

  • Moneyline: Cardinals -125, Diamondbacks +106
  • Run Line: Cardinals -1.5 (+164), Diamondbacks +1.5 (-200)
  • Over/Under: 7.5 runs

The Cardinals are favored with a 55% win probability, while the Diamondbacks stand at 45%. The predicted score leans towards a close game, with the Cardinals edging out a 5-4 victory.

Recent Game Recaps

In the series opener on May 23, the Cardinals secured a 4-3 win, capitalizing on a four-run sixth inning. The following day, they clinched a 6-5 victory, with Ryan Helsley striking out Eugenio Suárez to end the game.

Conclusion

As the Cardinals aim for a series sweep, their home advantage and recent form give them the upper hand. However, with Brandon Pfaadt on the mound, the Diamondbacks have a fighting chance to turn the tide. Expect a tightly contested game with potential playoff implications.

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